The RAT ANTI MOUSE CD11b Antibody from MyBioSource.com is a Rat Monoclonal antibody to CD11b, CD11b / CD18, CD11b/CD18, integrin alpha M, ITGAM, Ly-40, and MAC1. This antibody recognizes Mouse antigen. The RAT ANTI MOUSE CD11b Antibody has been validated for the following applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry, and Immunoprecipitation.
Description
Rat anti Mouse CD11b antibody, clone 5C6 recognizes CD11b, also known as the integrin alpha M chain. CD11b is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. MBS216530 immunoprecipitates a heterodimer of 165 and 95kD. Rat anti Mouse CD11b antibody, clone 5C6 exhibits various functional properties, reportedly inhibiting adhesion in vitro and inflammatory recruitment in vivo. Rat anti Mouse CD11b antibody, clone 5C6 also inhibits delayed hypersensitivity, potentiates bacterial infections and inhibits type 1 diabetes